Last five dissidents leave Cuba
Jorge Luis Gonzalez, 39, Blas Giraldo Reyes, 54, Jose Ubaldo Izquierdo, 44, Jesus Mustafa, 66, and 47-year-old Antonio Diaz boarded a commercial flight that will arrive in the Spanish capital on Friday, an embassy spokesman said.
Izquierdo, however, may take another flight out of Madrid for Chile, after Santiago on Monday said it would welcome him and his family.
The five dissidents completed the list of 20 who have accepted residency in Spain after Spain helped broker a deal reached on July 7 between the Cuban government and the Roman Catholic Church to gradually free 52 detainees.
The remaining prisoners will remain in Cuba or leave for the United States.
The US Interest Section in Havana on Tuesday offered refugee status to all freed dissidents and their families who wish to travel to the United States and began interviewing prospective immigrants.
Cuba's parliamentary chief Ricardo Alarcon has said the country was ready to release more detainees.